An airstrike on a maternity hospital in the port city of Mariupol wounded women waiting to give birth and buried children in the rubble as Russian forces intensified their siege of Ukrainian cities.
The World Health Organisation (WHO) said on Wednesday that it has confirmed 18 attacks on medical facilities since the Russian invasion began two weeks ago.
Ukrainian officials said the attack at a medical complex in Mariupol wounded at least 17 people.
The ground shook more than a mile away when the series of blasts hit. Explosions blew out windows and ripped away much of the front of one building. Police and soldiers rushed to the scene to evacuate victims, carrying a bleeding woman with a swollen belly on a stretcher past burning and mangled cars.
Another woman wailed as she clutched her child. In the courtyard, a blast crater extended at least two stories deep.
“Today Russia committed a huge crime,” said Volodymir Nikulin, a top regional police official, standing in the ruins. “It is a war crime without any justification.”
In Zhytomyr, a city of 260,000 to the west of Kyiv, bombs fell on two hospitals, one of them a children’s hospital, mayor Serhii Sukhomlyn said on Facebook. He said there were no injuries.
President Volodymyr Zelensky said the Mariupol strike trapped children and others under debris.
“A children’s hospital. A maternity hospital. How did they threaten the Russian Federation?” Mr Zelensky asked in his nightly video address, switching to Russian to express horror at the strike.
“What kind of country is this, the Russian Federation, which is afraid of hospitals, afraid of maternity hospitals, and destroys them?”
He urged the West to impose even tougher sanctions, so Russia “no longer has any possibility to continue this genocide”.
Video shared by Mr Zelensky showed cheerfully painted hallways strewn with twisted metal.
“There are few things more depraved than targeting the vulnerable and defenceless,” British Prime Minister Boris Johnson tweeted, adding that Russian President Vladimir Putin will be held “to account for his terrible crimes”.
The WHO said it had confirmed 10 deaths in attacks on health facilities and ambulances since the fighting began. It was not clear if its numbers included the assault on the maternity hospital.
US Secretary of State Antony Blinken condemned Russia’s “unconscionable attacks” in a call with his Ukrainian counterpart, Dmytro Kuleba, the US State Department said.
Two weeks into Russia’s assault on Ukraine, its military is struggling more than expected, but Mr Putin’s invading force of more than 150,000 troops retains possibly insurmountable advantages in firepower as it bears down on key cities.
Despite often heavy shelling on populated areas, American military officials reported little change on the ground over the previous 24 hours, other than Russian progress against the cities of Kharkiv and Mykolaiv, in heavy fighting. The officials spoke on condition of anonymity to assess the military situation.
Authorities announced new ceasefires to allow thousands of civilians to escape bombarded towns. Mr Zelensky said three humanitarian corridors operated on Wednesday, from Sumy in the northeast near the Russian border, from suburbs of Kyiv and from Enerhodar, the southern town where Russian forces took over a large nuclear plant.
In all, he said, about 35,000 people got out. More evacuations were planned for Thursday.
People streamed out of Kyiv’s suburbs, many headed for the city centre, as explosions were heard in the capital and air raid sirens sounded repeatedly. From there, the evacuees planned to board trains bound for western Ukrainian regions not under attack.
Civilians leaving the Kyiv suburb of Irpin were forced to make their way across the slippery wooden planks of a makeshift bridge, because the Ukrainians blew up the concrete span leading to Kyiv days ago to slow the Russian advance.
Previous attempts to establish safe evacuation corridors over the past few days largely failed because of what the Ukrainians said were Russian attacks. But Mr Putin, in a telephone call with Germany’s chancellor, accused militant Ukrainian nationalists of hampering the evacuations.
In Mariupol, a city of 430,000 people on the Sea of Azov, local authorities hurried to bury the dead from the past two weeks of fighting in a mass grave.
About 1,200 people have died in the nine-day siege of the city, Mr Zelensky’s office said.
Nationwide, thousands are thought to have been killed, both civilians and soldiers, since Mr Putin’s forces invaded. The UN estimates more than 2 million people have fled the country, the biggest exodus of refugees in Europe since the end of the Second World War.
The fighting knocked out power to the decommissioned Chernobyl nuclear plant, raising fears about the spent radioactive fuel that is stored at the site and must be kept cool. But the UN nuclear watchdog agency said it saw “no critical impact on safety” from the loss of power.
The crisis is likely to get worse as Moscow’s forces step up their bombardment of cities in response to what appear to be stronger Ukrainian resistance and heavier Russian losses than anticipated.
The Biden administration warned that Russia might seek to use chemical or biological weapons in Ukraine. The White House rejected Russian claims of illegal chemical weapons development in the country it has invaded.
This week, Russian Foreign Ministry spokeswoman Maria Zakharova — without evidence — accused Ukraine of running chemical and biological weapons labs with US support.
White House press secretary Jen Psaki called the claim “preposterous” and said it could be part of an attempt by Russia to lay the groundwork for its own use of such weapons against Ukraine.
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