Chris Webb won Blackpool South with 10,825 votes as the Tories were adrift in second with 3,218 votes.
"The narrative developing so far is one of large Conservative losses."
It is three years since the Tories last gained a seat at a by-election.
The Conservatives finished second, narrowly holding off Reform UK.
The FDA union has launched legal action claiming a decision to ignore orders from the European Court of Human Rights would breach civil service rules.
One protester said they would “find any way to stop the coach from moving, whatever that looks like”.
Under new laws, the Veterans ID card is not deemed an accepted form of ID for voting in UK elections.
Trump’s remarks at events in the battleground states of Wisconsin and Michigan were being closely watched after he was fined.
'This is low, even for you.' said on X user.
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